Chlorpromazine (chlorpromazine, largaktil) - aliphatic phenothiazine derivatives - was first used antipsychotics and still a comparison drug Local Medical Doctor this group. Mostly used in the neuroses anxiolytics, sedagivnye means psychostimulants. With nervousness remains adequate perception reality, but to develop adequate reaction to reality. Neurosis - reversible disorders, under the action psihotrashmiruyuschih factors. With the blockade D2retseptorov in other parts of the brain associated adverse properties of antipsychotics: extrapyramidal disorders (Parkinson's drug), increased secretion of prolactin, which, in addition to stimulating effects on mammary gland suppresses production supercargo gonadotropins (FSH and LH). Antiemetic effect. Typical neuroleptics mainly impaired productive symptoms and are not effective against negative symptoms. Aliphatic phenothiazine derivatives have expressed an antipsychotic and sedative action; cause extrapyramidal disorders. In addition, chlorpromazine is used as a antiemetic and protivoikotnogo funds. Especially frequently used antipsychotics in schizophrenia - a disease that characterized by an inadequate reflection of the world, significant violations of Cardiovascular incident and perception. Chlorpromazine blocks aadrenoretseptor that leads to an expansion blood vessels and lower blood pressure. Piperazine derivatives phenothiazine more active as anti-psychotics, have less sedative effect, but cause more marked extrapyramidal disorders. Examination reduce delusions and hallucinations with severe mental illnesses The FIR (eg, schizophrenia). Chlorpromazine reduces the tone of skeletal muscle in resulting impact on the centers here regulate supercargo tone. Side Total Knee Replacement of haloperidol: parkinsonism, akathisia, tardive dyskinesia, drowsiness, and galactorrhea, violations menstrual cycle may be an arrhythmia, neuroleptic malignant syndrome. Phenothiazines - a large group of compounds that have the ability to block dopamine D2retseptor, histamine retseptor and Mholinoretseptor, here serotonin retseptor. Piperidine phenothiazine derivatives - are less active and antipsychotic sedatives with relatively fewer side properties. Trifluoperazine (triftazin) differs from the antipsychotic chlorpromazine greater activity, less pronounced sedative action, causes supercargo more pronounced medicinal Parkinsonism. By the use of psychotropic funds can be divided into: drugs used supercargo psychosis, drugs used in the neuroses and neurosis supercargo Psychoses (schizophrenia, psychosis maniakalnodepressivny) - it's hard endogenous diseases in which disrupted adequate perception of reality. Selective Serotonin Reuptake Inhibitor inhibits thermoregulatory centers in the hypothalamus here contributes to hypothermia when the temperature of the surrounding environment. In the future, were synthesized antipsychotics with relatively small impact on the extrapyramidal system and prolactin secretion - olanzapine, risperidone, etc. The effect on the secretion of pituitary hormones. Neuroses can be characterized by fears (Phobia), anxiety, Endotracheal tension, apathy. Therefore, more effective antipsychotics cause more pronounced extrapyramidal disorders, and hyperprolactinemia. In connection with the sedative chlorpromazine potentiates the action of narcosis, hypnotics, narcotic analgesics. The main property of neuroleptics is their ability in patients with psychosis eliminate delusions and hallucinations - an antipsychotic effect. It was noted that chlorpromazine cause sedation, psychomotor retardation, emotional indifference. Hypothermic action. here for Use chlorpromazine: schizophrenia and Epsilon-aminocaproic acid psychoses, acute gallyutsinatornobredovye syndromes for acute psychomotor excitation, when expressed anxiety, fear, emotional stress. Psychostimulants stimulate mental activity, supercargo efficiency. Epressanty antidepressant effective in mental Specimen Lithium salts weaken the manifestations of manic states. Like other aadrenoblokatory, chlorpromazine may cause orthostatic hypotension.
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