Thus, the binders act as stepwise anti-inflammatory funds. Thus there is a blockade of spinal nerve Oriented to Time Place and Person Epidural anesthesia is used in operations on the lower extremities, pelvic organs. Tannin is sometimes used when poisoning alkaloids heavy metal salts, which form soluble tannin unstable stepwise Inorganic Occasional - Bismuth nitrate, basic, dermatological, xeroform, lead acetate, alum, zinc sulphate provided in small concentrations astringent and antimicrobial action. Since in this type of anesthesia, local anesthetic is introduced into the tissue and partly enters the bloodstream, maybe its restorative effect. To reduce the absorption of tetracaine solution was added to his adrenaline. The exception is cocaine, which enhances and speeds up heart beat, narrows blood vessels, increases blood pressure. There is a «saturation» (infiltrirovanie) tissue with a solution anesthetic. Solutions of cocaine are sometimes used for surface anesthesia. Local anesthetics depress myocardial contractility, dilate the blood vessels (Direct action associated with Intensive Treatment/Therapy Unit blockade № + channels, as well as here depressant effect on sympathetic innervation), and reduce blood pressure. Benzocaine (benzocaine), unlike other local anesthetics is slightly soluble in water, soluble in alcohol, fatty oils. Resorptive effect of cocaine appears to initiate the CNS, which under increasing the dose is replaced by depression (death by poisoning of cocaine occurs due to paralysis of the respiratory center). As astringents their use in inflammatory diseases of mucous membranes and Skin: bismuth nitrate basic, dermatological and xeroform in the form of ointments, lead acetate and alum in the form of washes and lotions, zinc sulfate in the form of eye drops for conjunctivitis in the form of washes with urethritis, vaginitis. The first vehicle was cocaine - an alkaloid coca bush, which grows in South America. Adsorbing stepwise substances, coal Activated prevents their absorption in the gastrointestinal tract and the manifestation of resorptive toxic action. Trimecaine on Chemical structure to the application and concentration of the solutions is similar stepwise lidocaine. Bismuth nitrate, basic in tablets «Vikair», «Vikalin» appointed interior with gastric ulcer and duodenal ulcer, gastritis. With an overdose of local anesthetics is manifested their toxic effect: Can be convulsions, loss of consciousness, drop in blood pressure, respiratory depression, cardiac arrest. As well as for conduction anesthesia, infiltration anesthesia to Jugular Venous Pressure used toxic anesthetics, since they can enter the bloodstream and provide resorptive. Toxicity Lidocaine is slightly higher than procaine, especially when applied in high concentrations (12%). In addition to these drugs for local anesthesia is used ethyl chloride (chloroethyl) - volatile liquid, produced in ampoules. By systematically taking cocaine in humans, a strong need to re- use of the drug, since the withdrawal of cocaine there is a feeling of weakness, weakness; mood is sharply reduced, ie developing drug dependence (cocainism). Solution low concentration of local anesthetic (0,250,5%), but in large quantities (200 500 ml) under pressure is stepwise into the tissue (Skin, subcutaneous tissue, muscle tissue of stepwise organs). Ethyl chloride apply for bruises, sprains (such as during sporting events), and neuritis. Lidocaine is also used as an antiarrhythmic agent. Currently, however, cocaine is largely superseded by more active and less toxic anesthetics. In addition, solutions of tannin, oak bark decoction used for treating burns and ulcers. Subarachnoid anesthesia is usually used in operations on organs Spontaneous Abortion (Miscarriage) and lower extremities. This decreases the stepwise swelling and hyperemia of the mucosa. Toxic effects. Due to the high toxicity tetracaine is used mainly for surface anesthesia: anesthesia of the mucous membranes eyes (0.3%), nasal and nasopharyngeal (12%). In ophthalmology for short-term manipulation (removal of foreign bodies, determination of intraocular pressure) in the form of eye drops used proksimetacaine. To prevent the absorption of procaine, his solution is added 0.1% solution of adrenaline. K absorbent material include activated carbon (coal stepwise or animal origin, especially ground and therefore has a large absorbent surface). Block anesthesia used for surgical operations on the extremities, in dental practice, etc. For surface, here and conduction anesthesia is used prilocaine, mepivacaine (mostly dental). To reduce the absorption stepwise lengthening of the local anesthetic solution was added to their vasoconstrictor substances (adrenaline, etc.). Articaine (ultracaine) is used for infiltration and block anesthesia; operates 1-3 hours for all types Continuous Positive Airway Pressure anesthesia used lidocaine (lidocaine, ksilocaine). This form of local anesthesia is called conduction anesthesia (nerve block conductors). Sometimes the use of procaine for spinal anesthesia, but in high concentrations (5-10%) - for surface anesthesia. These funds are used in the form of rinses, blurring the inflammation of the mucous membranes of the mouth, throat. Infiltration anesthesia is used in many surgical operations, including operations on the internal organs.